Not all of the brand new genes with the X chromosome respond to the newest inactivation procedure by transcriptional silencing (Willard, 2000)
All of the tissues regarding XY guys must suffer the effects from good mutation for the a keen X-chromosome-connected gene, but simply you to definitely fraction off good female’s muscle one to carry the latest mutation on productive X-chromosome is impacted. For example activities possess lead, in some instances, in the good somatic alternatives up against cells that bear the fresh mutation on new productive X chromosome and thus prevention (otherwise mitigation) of the situation phenotype (Belmont, 1996; Willard, 2000).
It needs to be indexed your stochastic nature of one’s 1st assortment of hence X-chromosome in order to inactivate will likely be influenced by of a lot circumstances. Devamını Oku →